R. Mark Richardson, MD, PhD, FAANS

Assistant Professor
Director, Adult Epilepsy and Movement Disorders Surgery
Director, Brain Modulation Laboratory
Faculty Member, Center for the Neural Basis of Cognition

R. Mark Richardson




R. Mark Richardson, MD, PhD, FAANS, is director of Epilepsy and Movement Disorders Surgery at UPMC Presbyterian.

Dr. Richardson received his undergraduate education at the University of Virginia. He completed his medical and doctoral education in the MD/PhD program at the Medical College of Virginia, where his interest in adult neurogenesis led to an NIH National Research Service Award.

Prior to joining the faculty at the University of Pittsburgh in 2011, Dr. Richardson completed neurosurgical residency at the University of California San Francisco where he received specialized training in epilepsy neurosurgery, deep brain stimulation, and brain mapping during awake craniotomies. Additionally, he received an NIH National Research Service Award to study gene therapy delivery to the brain.

Dr. Richardson’s clinical specialization is comprehensive epilepsy surgery and deep brain stimulation for movement disorders. He started the interventional-MRI DBS program at UPMC, and his additional clinical expertise includes intraoperative mapping to preserve brain function, including language, in patients who are awake during epilepsy and tumor surgery.

Please also visit Dr. Richardson's Facebook page.

Specialized Areas of Interest

Epilepsy surgery, deep brain stimulation for movement and limbic disorders (including interventional-MRI guided DBS surgery), awake surgery in eloquent brain areas.

Board Certifications

American Board of Neurological Surgeons

Hospital Privileges

UPMC Presbyterian
UPMC Hamot

Professional Organization Membership:

American Association of Neurological Surgeons
American Association of Stereotactic and Functional Neurosurgery
American Epilepsy Society
American Society for Neural Transplantation and Repair
Congress of Neurological Surgeons
International Movement Disorders Society
Society for Neuroscience 

Education & Training

BA, University of Virginia, 1997
MD/PhD, Medical College of Virginia, 2005
Fellowship, University of California San Francisco Postdoctoral Fellowship, 2010
Residency, University of California San Francisco Neurological Surgery, 2011

Honors & Awards

Faculty Teaching Award, Department of Neurological Surgery, 2013
Pittsburgh’s Best Doctors, Pittsburgh Magazine, 2016

Selected Publications

Modo M, Hitchens TK, Liu JR, Richardson RM. Detection of aberrant hippocampal mossy fiber connections – ex vivo mesoscale diffusion MRI and micro-tractography with histological validation in a patient with uncontrolled temporal lobe epilepsy. Hum Brain Mapp 37(2):780-95, 2016.

Alhourani A, McDowell MM, Randazzo M, Wozny T, Kondylis E, Lipski WJ, Beck S, Karp JF, Ghuman AS, Richardson RM. Network Effects of Deep Brain Stimulation. J Neurophysiol 114(4):2105-17, 2015.

Randazzo MJ, Kondylis ED, Alhourani A, Wozny TA, Lipski WJ, Crammond DJ, Richardson RM. Three-Dimensional Localization of Cortical Electrodes in Deep Brain Stimulation Surgery from Intraoperative Fluoroscopy. Neuroimage 125:515-521, 2015.

Lipski WJ, DeStefino VJ, Stanslaski SR, Antony AR, Crammond DJ, Cameron JL, Richardson RM. Sensing-Enabled Hippocampal Deep Brain Stimulation In Idiopathic Nonhuman Primate Epilepsy. J Neurophysiol 113:1051-1062, 2015. 

Kondylis ED, Wozny TA, Lipski WJ, Popescu A, DeStefino VJ, Esmaeili B, Raghu VK, Bagic A, Richardson RM. Detection of high-frequency oscillations by hybrid depth electrodes in standard clinical intracranial EEG recordings. Front Neurol 5:149, 2014.

Ghuman AS, Brunet NM, Li Y, Konecky RO, Pyles JA, Walls SA, Destefino V, Wang W, Richardson RM. Dynamic encoding of face information in the human fusiform gyrus. Nature Commun 8;5:5672, 2014.

Richardson RM, Freed CR, Starr PS. Pallidal neuronal discharge in Parkinson’s disease following intraputamenal fetal mesencephalic allograft. J Neurol Neurosurg Psychiatry 82(3):266-71, 2011

Richardson RM, Kells AP, Martin AJ, Larson PS, Starr PA, Piferi PG, Bates G, Tansey L, Rosenbluth KH, Bringas JR, Berger MS, Bankiewicz KS. Novel Platform for MRI-guided Convection-enhanced Delivery of Therapeutics: Preclinical validation in nonhuman primate brain. Stereotact Funct Neurosurg 89(3):141-151, 2011

Richardson RM, Kells AP, Rosenbluth KH, Aguilar Salegio E, Fiandaca MS, Larson PS, Starr PA, Martin AJ, Lonser RR, Federoff HJ, Forsayeth JR, Bankiewicz KS. Interventional MRI-Guided Putaminal Delivery of AAV2-GDNF for a Planned Clinical Trial in Parkinson's Disease. Mol Ther 19(6):1048-57, 2011.

Richardson RM, Ostrem JL, Starr PA. Surgical Repositioning of Misplaced Subthalamic Electrodes in Parkinson's Disease: Location of Effective and Ineffective Leads. Stereotact Funct Neurosurg 87(5):297-303, 2009.

A complete list of Dr. Richardson's publications can be reviewed through the National Library of Medicine's publication database.

Media Appearances

Brain Surgery Option Now For Patients Crippled By Severe OCD
August 31, 2016
CBS TV-2, New York

Epilepsy Research Leads To New Insights Into How Our Brains Read
August 16, 2016
WESA Radio Pittsburgh Tech Report

Deep Brain Stimulation Could Help Patients With Severe OCD
July 13, 2016
KDKA-TV Evening News

Parkinson’s patients find relief through surgery
June 2, 2016
Oregon's The Bulletin

Neurobiology of Deep Brain Stimulation
April 27, 2016
Journal of Neurophysiology Podcasts

Deep-brain stimulation helps Erie Parkinson's patients
March 26, 2016

Pitt professor's gene therapy trial holds promise for Parkinson's patients
February 29, 2016
Pittsburgh Tribune-Review

Local Doctor Leads Study Of Gene Therapy Treatment For Parkinson’s Patients
February 18, 2016

Neurotechnology offers new solutions to treating brain diseases
January 26, 2016

Neurosurgeons using laser technology to eradicate brain tumors
November 9, 2015
Pittsburgh Tribune-Review

McCandless woman 1st in region with implant aimed at halting seizures
August 2, 2015
Pittsburgh Tribune-Review

Richardson Discusses Epilepsy
June 8, 2015
KDKA Radio Morning News

Functional neurosurgery for improving quality of life (pdf)
September 2014
Allegheny County Medical Society Bulletin

UPMC procedure offers hope for severe OCD cases
August 11, 2014
Pittsburgh Post-Gazette

Health Beat: Parkinson's: Stop the shaking
June 5, 2014
WFMZ-TV 69 (Lehigh Valley, Pa.)

Parkinson’s: Stop the shaking
May 28, 2014
WWSB-TV 7 (Sarasota, Fla.)

Breakthrough Parkinson's treatment stops the shaking
May 27, 2014
WNDU-TV (South Bend, Ind.)

Pittsburgh chef Pais honored at James Beard fundraiser dinner at Art Institute
Pittsburgh Tribune-Review

May 27, 2014

Parkinson’s: Stop The Shaking
May 14, 2014
NewsChannel5.com (Nashville, Tenn.)

New technique minimizes tremors in Parkinson's patient
May 4, 2014
News4Jax.com (Jacksonville, Fla.)

Richardson Discusses Parkinson's and DBS
April 30, 2014
KDKA Radio Morning News

Brain Pacemaker
September 23, 2013
The Cure

'Brain pacemaker' may slow effects of Alzheimer's
March 19, 2013
NBC todayhealth.today.com

A return to normalcy for Shadyside chef Toni Pais
March 17, 2013
Pittsburgh Post-Gazette 

Epilepsy Surgery
August 15, 2012
Discovery Channel

UPMC OnTopic Discussions

Adult Epilepsy Surgery
Dr. Richardson discusses the benefits of epilepsy surgery for adult patients.