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Basic Science Projects

Effects of Traumatic Brain Injury in Alpha Synuclein and Dopamine Regulation

Funding Agency:

National Institute of Health

Total Project Period:

4/1/10 - 3/31/15

Total Project Award:

$231,900

Principal Investigator:

Samuel S. Shin

Mentor: 

C. Edward Dixon, PhD

Project Summary:

This research investigates how the loss of regulation of neurotransmitter dopamine occurring after TBI may be due to the affects of pathological changes in alpha-synuclein protein. Understanding this mechanism will help us develop therapeutic strategies to treat functional deficits after TBI and possible future development of neurodegenerative diseases.

Dr. Dixon