Funding Agency:

The Pittsburgh Foundation

Total Project Period:

7/1/08 - 6/30/10

Total Project Award:

$17,500

Principal Investigator:

Nestor D. Tomycz, MD

Project Summary:

Continuous intrathecal delivery of antioxidants and heavy metal chelators as a novel neurosurgical strategy for the prevention of detrimental oxidation in the central nervous system. A preliminary investigation of safety, neuropathological consequences, and behavioral outcomes using a mouse model of Alzheimers Disease.