Funding Agency:

National Institute of Health

Total Project Period:

7/01/08 - 6/30/13

Total Project Award:

$113,035

Principal Investigator:

Hulya Bayir, MD

Co-Investigator:

C. Edward Dixon, PhD

Project Summary:

This project will identify oxidative phospholipids functioning as signaling molecules in neuronal death after TBI using state of the art lipidomics approach. We will test novel compounds in experiments to prevent oxidative stress and neuronal death after TBI. The ability to selectively modulate this pathway could lead to targeted therapies for TBI and ultimately improve outcome for children.