Donald J. Crammond, PhDAssistant Professor of Neurological Surgery
Associate Director, Movement Disorder Surgery
Donald Crammond, PhD, joined the Center for Clinical Neurophysiology as a staff neurophysiologist in November 1998.
Dr. Crammond received his undergraduate education in physiology at the University of Glasgow in Scotland and his graduate education in neurophysiology at the University of Toronto. After postdoctoral studies at the University of Wisconsin and later at the Université de Montréal, he was appointed Visiting Associate Scientist at the National Institute of Mental Health in Bethesda, MD.
Dr. Crammond specializes in behavioral and systems-level neurophysiology, examining the neuronal substrates of visuomotor and higher cognitive processes in the cerebral cortex and the mechanisms underlying motor learning and movement disorders. Dr. Crammond is the associate director for microelectrode recording for the Movement Disorder Surgery Program at UPMC.
Dr. Crammond's publications can be reviewed through the National Library of Medicine's publication database.
American Board of Neurophysiological Monitoring
Children’s Hospital of Pittsburgh of UPMC
Magee-Womens Hospital of UPMC
UPMC Passavant Cranberry
UPMC St. Margaret
Professional Organization Membership
American Clinical Neurophysiology Society
American Society for Neurophysiological Monitoring
Society for the Neural Control of Movement
Society for Neuroscience
How You Move Your Arm Says Something About Who You Are
July 19, 2012
NPR All Things Considered
Dr. Crammond’s primary clinical research interest is in retrospectively reviewing clinical outcome data to determine the impact of various modalities of IONM to prevent and/or reduce iatrogenic injury. This is an ongoing effort that is important as IONM is a young specialty and guidelines are required to establish the clinical utility of IONM.
Dr. Crammond’s other major clinical research interest is to examine the utility of micro-electrode recording (MER) in finalizing the placement of Deep Brain Stimulating (DBS) elec-trodes. MER does improve the localization of DBS in the target structure, i.e., the subthalamic nucleus (STN) of PD patients. However, in addition to DBS localization, he is also examining whether there is any correspon-dence between post-operative DBS programming parameters and the associated therapeutic efficacy of DBS based on the knowledge of the precise location of the DBS electrodes in the STN of Parkinson’s Disease patients.
As part of a translational project, Dr. Crammond is recording from human dorsal root ganglion (DRG) cells during lumbar decompressive surgeries in an IRB approved study to determine the utility of DRG recordings for brain-machine interface research. This human subject research is based and built upon the work of Dr. Douglas Weber’s lab in animal models. Together, they are now attempting to determine the most suitable recording electrodes to be used in human subjects and to develop a device that may be implanted for post-operative studies.
Finally, Dr. Crammond is undertaking neurophysiological studies of somatosensory evoked potentials (SSEPs) and trans-cranial motor evoked potentials (Tc-MEPs) in a non-human primate model of median nerve regeneration in order to research the differential effect of nerve growth factors on afferent versus efferent axonal regeneration.