Paul A. Gardner, MDAssociate Professor
Executive Vice Chair, Surgical Services
Neurosurgical Director, Center for Skull Base Surgery
Paul A. Gardner, MD, joined the faculty at the University of Pittsburgh Department of Neurological Surgery in 2008 after completing his residency and fellowship training at the University of Pittsburgh. He completed his undergraduate studies at Florida State University, majoring in biochemistry, and received his medical degree from the University of Pittsburgh School of Medicine.
Dr. Gardner completed a two-year fellowship in endoscopic endonasal pituitary and endoscopic and open skull base surgery. His research has focused on evaluating patient outcomes following these surgeries and more recently on genomic analysis of rare tumors. In April of 2008, Dr. Gardner was named neurosurgical director of the Center for Minimally Invasive Cranial Base Surgery at the University of Pittsburgh Medical Center.
Dr. Gardner is co-author of the recently released book Skull Base Surgery, part of the Master Techniques in Otolaryngology: Head and Neck Surgery series published by Wolters Kluwer. The book offers step-by-step expert instruction on more than 45 procedures, covering both open and minimally invasive approaches to the skull base. In addition, he is an author on over 160 peer-reviewed articles.
Specialized Areas of Interest
Endoscopic endonasal and open skull base surgery; pituitary tumors; vascular surgery; cranial nerve disorders; minimally invasive surgery; peripheral nerve surgery.
American Board of Neurological Surgeons
Children’s Hospital of Pittsburgh of UPMC
Veterans Affairs Pittsburgh Healthcare System
Professional Organization Membership
American Association of Neurological Surgeons
American Medical Association
Congress of Neurological Surgeons
North American Skull Base Society
Pennsylvania Neurological Society
Pituitary Network Association
Education & Training
AA, Okaloosa-Walton College, 1993
BS, Biochemistry, Florida State University, 1997 (Magna Cum Laude)
MD, University of Pittsburgh, 2001
Fellowship, Min Inv endoNeurosurgery, 2007
Residency, Neurosurgery, University of Pittsburgh, 2008
Honors & Awards
Best Doctors, Pittsburgh Magazine, 2012-15
Tepedino MS, Pinheiro-Neto CD, Bezerra TF, Gardner PA, Snyderman CH, Voegels RL. Endonasal identification of the orbital apex. Laryngoscope 126(1):33-8, 2016.
Bleier BS, Castelnuovo P, Battaglia P, Turri-Zanoni M, Dallan I, Metson R, Sedaghat AR, Stefko ST, Gardner PA, Snyderman CH, Noguiera JF, Ramakrishnan VR, Muscatello L, Lenzi R, Freitag S. Endoscopic endonasal orbital cavernous hemangioma resection: global experience in techniques and outcomes. Int Forum Allergy Rhinol 6(2):156-61, 2016.
Rowan NR, Wang EW, Gardner PA, Fernandez-Miranda JC, Snyderman CH. Nasal deformities following nasoseptal flap reconstruction of skull base defects. J Neurol Surg B 77(1):14-18, 2016.
de Almeida JR, Carvalho F, Vaz Guimaraes FIlho F, Kiehl TR, Koutourousiou M, Su S, Vescan AD, Witterick IJ, Zadeh G, Wang EW, Fernandez-Miranda JC, Gardner PA, Gentili F, Snyderman CH. Comparison of endoscopic endonasal and bifrontal craniotomy approaches for olfactory groove meningiomas: A matched pair analysis of outcomes and frontal lobe changes on MRI. J Clin Neurosci 22(11):1733-41, 2015.
Gardner PA, Vaz-Guimaraes F, Jankowitz B, Koutourousiou M, Fernandez-Miranda JC, Wang EW, Snyderman CH. Endoscopic endonasal clipping of intracranial aneurysms: surgical technique and results. World Neurosurg 84(5):1380-93, 2015.
Wang WH, Abhinav K, Wang E, Snyderman C, Gardner PA, Fernandez-Miranda JC. Endoscopic endonasal transclival transcondylar approach for foramen magnum meningiomas: surgical anatomy and technical note. Neurosurgery [Epub ahead of print], 2015.
Mathias RN, Lieber S, Pires de Aguiar PH, Calfat Maldaun MV, Gardner P, Fernandez-Miranda JC. Interfascial dissection for protection of the nerve branches to the frontalis muscles during supraorbital trans-eyebrow approach: an anatomical study and technical note. J Neurol Surg B [Epub ahead of print], 2015.
Ying T, Thirumala P, Gardner P, Habeych M, Crammond D, Balzer J. The incidence of early postoperative conductive hearing loss after microvascular decompression of hemifacial spasm. J Neurolog Surg B 76(B6):411-5, 2015.
Kooshkabadi A, Choi PA, Koutourousiou M, Snyderman CH, Wang EW, Fernandez-Miranda JC, Gardner PA. Atlanto-occipital instability following endoscopic endonasal approach for lower clival lesions: Experience with 212 cases. Neurosurgery 77(6):888-97, 2015.
Gande AV, Chivukula S, Moossy JJ, Rothfus W, Agarwal V, Horowitz MB, Gardner PA. Long-term outcomes of intradural cervical dorsal root rhizotomy for refractory occipital neuralgia. J Neurosurg 18:1-9, 2015.
A complete list of Dr. Gardner's publications can be reviewed through the National Library of Medicine's publication database.
In a chordoma exome sequencing project, Dr. Gardner has identified promising germline changes in canonical p53 related genes and interesting tumor specific CNV losses in basic-helix-loop-helix (bHLH) E box binding (CANNTG) transcription factors critical for neural development and determination of neural cell fate. (IRX3: developmental neural pattern formation/ LEFTY1: required for let-right axis determination/ BHLHA9: syndactyly, mesoaxial synostosis/ LHX3: pituitary development and motor neuron specification/FOXH1: holoprosencephaly/RUNX3: adenoid cystic carcinoma). This is a rich subset of genes critical for normal neural development. In addition, the Notch pathway is involved which is also critical during development. All of this suggests that this tumor may arise from some sort of error in the neural development program for which these patients have a predisposition in germline DNA with CNV losses that drive tumorigenesis.
Neurogel project is a project with Dr. Bryan Brown in bioengineering evaluating a novel gel made from neural tissue that has been found to significantly promote the regrowth of injured peripheral nerves across gaps, both in vitro and in an animal model.
Surgery Workshop Held
October 17, 2015
The New Indian Express
Into another dimension: A local couple uses a 3-D printer to help diagnose and treat a brain tumor
February 4, 2015
San Luis Obispo County New Times
Search for less-invasive avenue for brain surgery leads to eyelid, UPMC surgical team
February 1, 2015
Woman has brain surgery through her Eyelid to prevent headaches after doctors said traditional surgery was too dangerous
January 27, 2015
London Daily Mail
Hard search for less invasive brain surgery leads to eyelid
January 27, 2015
Hard Search for Less Invasive Brain Surgery Leads to Eyelid
January 26, 2015
New York Times
Pioneering Surgery Saves 5-Year-Old's Life
December 16, 2009
KDKA-TV Evening News
Rare surgery to restore Jain Acharya's eyesight
March 6, 2009
A million well-wishers, 15 doctors point guru to Pittsburgh
February 12, 2009
UPMC On Topic Videos
Pituitary Adenomas and the Endoscopic Endonasal Approach
Dr. Gardner explains pituitary adenoma tumors and the experience his multidisciplinary team has in treating the tumor with the Endoscopic Endonasal Approach.
Craniopharyngiomas and the Endoscopic Endonasal Approach
Dr. Gardner explains craniopharyngioma tumors and the experience his multidisciplinary team has in treating the tumor with the Endoscopic Endonasal Approach.
Chordoma Tumors and the Endoscopic Endonasal Approach
Dr. Gardner explains chordoma tumors and the experience his multidisciplinary team has in treating the tumor with the Endoscopic Endonasal Approach.
Minimally Invasive Brain Surgery at UPMC
Dr. Gardner talks about the benefits of minimally invasive brain surgery at UPMC.