Stephanie Greene, MD

  • Associate Professor
  • Director, Vascular Neurosurgery, UPMC Children's Hospital of Pittsburgh
  • Director, Perinatal Neurosurgery, UPMC Children's Hospital of Pittsburgh
  • Director, Pediatric Neurosurgery Fellowship

Stephanie Greene, MD, is a nationally recognized expert in pediatric vascular neurosurgery and congenital neurosurgical disorders. She joined the faculty of the Department of Neurological Surgery in the pediatric neurosurgery division at UPMC Children’s Hospital of Pittsburgh in 2009. She was the director of pediatric neurosurgery at Hasbro Children’s Hospital, affiliated with Brown University, prior to accepting her position at UPMC Children’s Hospital of Pittsburgh. She is the director of vascular neurosurgery and perinatal neurosurgery at Children’s Hospital of Pittsburgh.

Dr. Greene graduated from Dartmouth College in 1993 with a degree in biology and psychology, and a concentration in neuroscience. She earned her medical degree from Albany Medical College, and completed her neurosurgical residency at Harvard University in the Brigham & Women’s and Children’s Hospital of Boston program. Dr. Greene received additional subspecialty fellowship training pediatric neurosurgery through the University of Washington at Seattle Children’s Hospital in 2005. She is board certified in both adult and pediatric neurosurgery. She is a fellow of the American Association of Neurological Surgeons and a member of the Congress of Neurological Surgeons and American Society of Pediatric Neurosurgeons

Dr. Greene's publications can be reviewed through the National Library of Medicine's publication database.

Specialized Areas of Interest

Vascular malformations; MoyaMoya syndrome; Chiari malformation; spinal dysraphism; peripheral nerve disorders; brain tumors; fetal surgery.

Board Certifications

American Board of Neurological Surgery
American Board of Pediatric Neurological Surgery

Hospital Privileges

UPMC Children's Hospital of Pittsburgh
UPMC Magee-Womens Hospital

Professional Organization Membership

American Association of Neurological Surgeons
American Society of Pediatric Neurosurgeons
AANS/CNS Joint Section on Pediatric Neurosurgery
AANS/CNS Joint Section on Tumors
Congress of Neurological Surgeons
Pediatric Craniocervical Society
Pennsylvania Neurological Society
Sigma Xi
Women in Neurosurgery
World Federation of Neurological Societies

Professional Activities

Abstract Reviewer, CNS Annual Meetings
Abstract Reviewer, AANS Annual Meetings
AANS Resident Mentorship Program
Steering Committee, North American Fetal Treatment Network
Grant Review Committee, Walter L. Copeland Fund, Pittsburgh Foundation
Oral Board Examiner, American Board of Neurological Surgeons

Education & Training

  • AB, Biology/Psychology, Dartmouth College, 1993
  • MD, Albany Medical College, 1998
  • Residency, Neurological Surgery, Penn State University, 2000
  • Residency, Neurological Surgery, Harvard University, 2004
  • Fellowship, Pediatric Neurological Surgery, 2005

Honors & Awards

  • Pittsburgh’s Best Doctors, Pittsburgh Magazine, 2021
  • Castle Connolly Top Doctor, 2016-present
  • Marquis Who’s Who in the World, 2018-present
  • Marquis Who’s Who in America, 2018-present
  • Castle Connolly Exceptional Women in Medicine, 2017-present
  • American’s Most Honored Professionals (American Registry), 2017-present
  • Castle Connolly Regional Top Doctor, 2017-present
  • Castle Connolly Metro Area Top Doctor, 2016-present
  • Top Ten Doctor – Metro Area, City, and State (, 2013-present
  • Patients’ Choice 5-Year Honoree, 2013-present
  • America’s Most Compassionate Doctors, 2011-present
  • Cambridge’s Who’s Who 2011 America’s Top Surgeons, 2007, 2011, 2012
  • Patients’ Choice Award, 2008-present

Research Activities

Dr. Greene is involved in several moyamoya studies including one identifying a noninvasive, radiation-free method of quantifying vascular reserve and a patient’s risk of stroke, both pre- and post-operatively.  Another study seeks to standardize the anesthetic management of these patients to minimize their perioperative stroke risk. Large series of patients with cavernous malformations and Chiari I malformation are being analyzed in preparation for publication. The outcomes of myelomeningocele patients with regard to shunt infection, shunt malfunction, and tethered cord syndrome are being described in separate publications. A study analyzing the outcomes of breech presentation in myelomeningocele is in progress. A study aiming to identify shunt malfunction in patients with slit ventricle syndrome continues to enroll patients. Several manuscripts describing the outcomes of standard post-natal treatment of congenital isolated aqueductal stenosis are nearing completion. Fetal surgery for isolated aqueductal stenosis is progressing toward humanitarian use: the shunt design has been patented, and initial studies are nearly complete.

Media Appearances

UPMC doctors perform life changing surgery to repair spinal defect
June 10, 2019
Lock Haven Express

In-utero Fetal Surgery Carried For the First Time Ever In Pittsburgh
June 10, 2019
Gobal Market News 24

Pitt Researchers Perform University’s First In Utero Spina Bifida Surgery
June 5, 2019

Pittsburgh Surgeons Repair Spina Bifida in Utero at 25 Weeks Gestation
June 5, 2019
Christian News

Doctors Operate on Baby Still in Mother's Womb
June 4, 2019
CNN/HLN Morning Express with Robin Meade

How Womb Surgery Saved A Baby From Being Born With A Birth Defect
June 4, 2019

Breakthrough in-utero surgery treats ‘devastating’ birth defect
June 3, 2019
New York Post

First-ever in-utero surgery to treat spina bifida
June 3, 2019

Thanks to surgery in the womb, newborn avoids devastating birth defect
June 2, 2019
WCTV-TV, Tallahassee, Fla.

Pittsburgh surgeons say results are good in their first spina bifida repair before baby is born
May 31, 2019
Pittsburgh Post-Gazette

Pittsburgh doctors perform first-of-its-kind in-utero fetal surgery to repair spina bifida
May 30, 2019

From the operating room to the pitcher's mound
April 19, 2019

Mt. Pleasant girl overcomes effects of brain surgery
March 5, 2014
Pittsburgh Tribune-Review

ADHD May Be Tied to Longer-Lasting Head Injury
June 25, 2013
U.S. News & World Report Health Day

UPMC Videos & Patient Stories

Surgical Treatment of Moyamoya in the Pediatric Population
Dr. Greene explains how surgical intervention is the only viable treatment to effectively halt neurological decline associated with moyamoya.

Brain Care Institute Patient Story: Nathan’s Story
See how one family found help for moyamoya through the expertise of Dr. Greene of the Brain Care Institute.